Hepatitis b virus polypeptides

Details Hepatitis b virus polypeptides Hepatitis b virus polypeptides

C - Chemistry, Metallurgy

07

K

C07K 19/00 (2006.01) A61K 38/16 (2006.01) A61K 39/29 (2006.01) A61K 39/385 (2006.01) A61K 48/00 (2006.01) C07K 14/02 (2006.01) C07K 14/33 (2006.01) C07K 16/08 (2006.01) C12N 1/21 (2006.01) C12N 15/36 (2006.01) C12N 15/62 (2006.01) C12N 15/63 (2006.01) C12N 15/70 (2006.01)

Patent

CA 2304255

The present invention provides a polypeptide comprising tetanus toxin fragment C, or a fragment thereof, fused to the pre-S1 region of hepatitis B virus (HBV), or a fragment thereof, and/or the pre-S2 region of HBV or a fragment thereof. It also provides vaccine compositions comprising the polypeptide of the invention.

La présente invention concerne un polypeptide comprenant un fragment C de toxine de tétanos ou un fragment de celui-ci condensé avec la région pré-S1 du virus de l'hépatite B (HBV) ou avec un fragment de celle-ci, et/ou avec la région pré-S2 de HBV ou un fragment de celle-ci. La présente invention concerne également des compositions de vaccin comprenant le polypeptide de l'invention.

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