W-aminoalkanoic acid arylamides

Details W-aminoalkanoic acid arylamides W-aminoalkanoic acid arylamides

C - Chemistry, Metallurgy

07

C

260/474.1, 260/4

C07C 69/78 (2006.01) A61K 31/16 (2006.01) A61K 31/165 (2006.01) A61K 31/245 (2006.01)

Patent

CA 1041535

ABSTRACT OF THE DISCLOSURE The present invention provides .alpha.-aminoalkanoic acid arylamides having the formula R'(CH2)n CONHR .............(I) wherein R represents a phenyl or naphthyl group which can be substituted with a halogen atom, or anitro, lower alkyl, lower alkoxyl, hydroxyl, acetoamino or lower alkoxycarbonyl group; R' represents an amino group and n is an integer of from 4 to 8 which have a blood platelet aggregation inhibiting effect, and are preventive and therapeutic medicines for thromlosis in encephalo- and cardio-vasculer system. The present invention also provides a process for their preparation.

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