C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 15/26 (2006.01) A61K 31/70 (2006.01)
Patent
CA 2203155
Derivatives of general formula (I), wherein R is an acyl grouping and R' is a hydrogen atom, a monoester phosphate residue or a substituted carbamate grouping, salt forms thereof and a preparation method therefor, are disclosed. The use of said water-soluble compounds as a drug, as well as for preparing a drug for treating cancer, is also disclosed.
La présente invention concerne des dérivés de formule générale (I), dans laquelle R représente un groupement acyl et R' représente soit un atome d'hydrogène soit un reste phosphate monoester, soit un groupement carbamate substitué, et ses formes salifiées, et son procédé de préparation. Elle concerne ainsi l'utilisation de ces composés hydrosolubles à titre de médicament, ainsi que pour la préparation d'un médicament destiné au traitement anticancéreux.
Guminski Yves
Hill Bridget
Imbert Thierry
Monse Barbara
Robin Jean-Pierre
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Pierre Fabre Medicament
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