Wdrpuh epitope peptides and vaccines containing the same

Details Wdrpuh epitope peptides and vaccines containing the same Wdrpuh epitope peptides and vaccines containing the same

C - Chemistry, Metallurgy

07

K

C07K 7/06 (2006.01) C12N 5/0783 (2010.01) C12N 5/0786 (2010.01) A61K 39/00 (2006.01) A61P 35/00 (2006.01) C12N 15/09 (2006.01)

Patent

CA 2745408

The present invention provides peptides containing the amino acid sequence of SEQ ID NOs: 1, 2, 3, 4, 16, 17, 30, 31, 34, 36, 37, 40, 41, 45, 49, 55, 57 and 61, as well as peptides containing the above-mentioned amino acid sequences in which 1, 2, or several amino acid(s) are substituted, deleted, inserted or added, but still have cytotoxic T cell inducibility. The present invention also provides drugs for treating or preventing tumors, which drugs containing these peptides. The peptides of the present invention can also be used as vaccines.

La présente invention concerne des peptides contenant la séquence d'acides aminés correspondant aux SEQ ID NO: 1, 2, 3, 4, 16, 17, 30, 31, 34, 36, 37, 40, 41, 45, 49, 55, 57 et 61, ainsi que des peptides contenant les séquences d'acides aminés susmentionnées où un ou plusieurs acides aminés sont substitués, délétés, insérés ou ajoutés, en conservant un pouvoir inducteur de cellules T cytotoxiques. La présente invention concerne également des médicaments destinés au traitement prophylactique ou thérapeutique de tumeurs, lesdits médicaments contenant lesdits peptides. Les peptides selon la présente invention peuvent également être employés en tant que vaccins.

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