Wettable surface modified contact lens fabricated from an...

G - Physics – 02 – B

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18/106, 88/40

G02B 1/04 (2006.01) C08J 7/12 (2006.01)

Patent

CA 1290516

?? Wettable Surface Modified Contact Lens Fabricated From An Oxirane Containing Hydrophobic Polymer Abstract A contact lens possessing a wettable surface in its ocular aqueous environment of use fabricated from a hydrophobic addition polymer incorporating between about 0.5 and about 30 % by weight oxirane substituted units in the backbone thereof, wherein the outer surfaces of said lens contain an effective hydrophilicity inducing amount of a reaction product of said oxirane substituted units of the formula I, Image (I) wherein R is hydrogen or methyl; R1 is carbonyl or lower alkylene; n is 1 to 4; and R° is hydrogen or Image with a reactive water soluble nucleophile selected from an organic amine, alcohol, thiol, urea or thioures, or sulfite, bisulfite or thio- sulfate and the use thereof by placement in the eye of a patient in need of the same to correct vision defects of a refractive nature.

554093

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