Wnt proteins and detection and treatment of cancer

G - Physics – 01 – N

Patent

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G01N 33/574 (2006.01)

Patent

CA 2580803

The present specification provides, inter alia, methods of using Wnt and FZD proteins, genes, FZD and Wnt-specific antibodies and probes in diagnosis and treatment of cancer and for screening test compounds for an ability to treat cancer. Also disclosed are compounds useful for treating cancer such as liver cancer.

La présente invention se rapporte notamment à des procédés d'utilisation de protéines Wnt et FZD, de gènes, d'anticorps dirigés contre FZD et Wnt, et de sondes associées, pour diagnostiquer et traiter un cancer, et pour détecter la capacité de composés d'essai à traiter un cancer. L'invention concerne également des composés utiles pour traiter un cancer tel qu'un cancer du foie.

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