Xanthine derivatives as selective hm74a agonists

Details Xanthine derivatives as selective hm74a agonists Xanthine derivatives as selective hm74a agonists

C - Chemistry, Metallurgy

07

D

C07D 473/06 (2006.01) A61K 31/495 (2006.01) A61P 3/00 (2006.01) A61P 9/00 (2006.01) C07D 473/04 (2006.01)

Patent

CA 2618963

The present invention relates to compounds 0f formula (I), which are xanthine derivatives, processes for the manufacture of said derivatives, pharmaceutical formulations containing the active compounds and the use of the compounds in therapy, for example, in the treatment of diseases where under-activation of the HM74A receptor contributes to the disease or where activation of the receptor will be beneficial.

La présente invention concerne des composés de formule (I) qui constituent des dérivés de xanthine, des procédés de fabrication desdits dérivés, des préparations pharmaceutiques contenant les composés actifs et l'utilisation desdits composés en thérapie, par exemple, dans le traitement de maladies, au cours desquelles la sous-activation du récepteur HM74A favorise la maladie ou bien l'activation du récepteur est bénéfique.

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