Ykl-40 as a marker and prognostic indicator for cancers

Details Ykl-40 as a marker and prognostic indicator for cancers Ykl-40 as a marker and prognostic indicator for cancers

G - Physics

01

N

G01N 33/574 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2343972

This invention provides methods for detecting cancers and for evaluating the prognosis of cancer patients. In particular, the methods of this invention utilize YKL-40 as a marker for the presence or absence of a cancer and for the prognosis (e.g. likelihood of recurrence) of a cancer. Elevated levels of YKL- 40 are indicative of the presence of a cancer in undiagnosed subjects and indicate likely recurrence of the cancer in subjects diagnosed as having a cancer.

L'invention concerne des procédés relatifs à la détection du cancer et à l'indication du pronostic pour les patients atteints du cancer. En particulier, les procédés décrits font appel au niveau de YKL-40 en tant que marqueur par rapport à la présence ou à l'absence de cancer et en tant qu'indicateur de pronostic (par exemple, probabilité de rechute). Des niveaux élevés de YKL-40 indiquent la présence d'un cancer chez les sujets n'ayant pas fait l'objet d'un diagnostic, et ils indiquent la possibilité d'une rechute chez les sujets ayant fait l'objet d'un diagnostic de cancer.

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