Ykl-40 as a marker for selection of treatment and monitoring...

Details Ykl-40 as a marker for selection of treatment and monitoring... Ykl-40 as a marker for selection of treatment and monitoring...

G - Physics

01

N

G01N 33/53 (2006.01) G01N 33/574 (2006.01) G01N 33/58 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2737274

The present invention relates to a methods for selecting a treatment for a specific disease or disorder, together with a method of monitoring therapeutic treatment of a specific disease or disorder and a method of determining a prognosis for a subject before, during and after administering a treatment by determining the level of YKL-40 in a sample obtained from the subject and comparing said level with one or more reference levels of YKL-40. The reference level is typically a level obtained from healthy individuals or a level previously obtained from the same subject. The present invention further relates to a kit and a device that may be used in the methods of the present invention.

La présente invention concerne un procédé de sélection dun traitement pour une maladie ou un trouble spécifique, ainsi quun procédé de surveillance dun traitement thérapeutique ou dune maladie ou dun trouble spécifique et un procédé de détermination dun pronostic pour un sujet avant, pendant et après ladministration dun traitement par détermination du niveau dYKL-40 dans un échantillon prélevé sur le sujet et par comparaison dudit niveau avec un niveau de référence dYKL-40 ou plus. Le niveau de référence est typiquement un niveau obtenu dindividus sains ou un niveau préalablement obtenu du même sujet. La présente invention concerne en outre un kit et un dispositif qui peuvent être utilisés dans les procédés de la présente invention.

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