Zero-order sustained released dosage forms and method of...

Details Zero-order sustained released dosage forms and method of... Zero-order sustained released dosage forms and method of...

A - Human Necessities

61

K

A61K 9/00 (2006.01) A61K 9/20 (2006.01) A61K 9/28 (2006.01)

Patent

CA 2470636

The present invention relates to zero-order sustained release solid dosage forms suitable for administration of a wide range of therapeutically active medicaments, especially those that are water-soluble, and to a process of making same. The solid dosage form comprises (a) a matrix core comprising ethylcellulose and the active agent and (b) a hydrophobic polymer coating encasing the entire matrix core.

L'invention concerne des formes dosifiées solides à libération soutenue d'ordre zéro appropriées à l'administration d'une large gamme de médicaments thérapeutiquement actifs, en particulier ceux solubles dans l'eau; ainsi qu'un procédé de production associé. La forme dosifiée solide comprend (a) un noyau matriciel contenant de l'éthylcellulose et un principe actif, et (b) un enrobage polymère hydrophobe renfermant la totalité du noyau matriciel.

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