Zilpaterol enantiomer compositions and methods of making and...

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 487/06 (2006.01) A23K 1/16 (2006.01) A61K 31/551 (2006.01)

Patent

CA 2656312

This invention is directed generally to zilpaterol enantiomer compositions, and, in particular, to compositions comprising the 6R, 7R zilpaterol enantiomer in an amount that is greater than that of any other enantiomer. This invention is also directed to processes for making such compositions; methods for using such compositions to, for example, increase the rate of weight gain, improve feed efficiency, and/or increase carcass leanness in livestock, poultry, and/or fish; and uses of such compositions to make medicaments. This invention is further directed to methods for determining the absolute configurations of zilpaterol enantiomers.

La présente invention a généralement trait à des compositions d'énanciomère de zilpaterol et, en particulier, à des compositions comprenant l'énanciomère de zilpaterol 6R, 7R suivant une quantité qui est supérieure à celle de tout autre énanciomère. La présente invention a également trait à des procédés permettant de fabriquer de telles compositions ; des procédés permettant d'utiliser de telles compositions pour, par exemple, augmenter le taux de prise de poids, améliorer l'efficacité alimentaire et/ou augmenter la maigreur de la carcasse chez le bétail, la volaille et/ou le poisson ; et des utilisations de telles compositions pour fabriquer des médicaments. La présente invention a en outre trait à des procédés permettant de déterminer les configurations absolues des énanciomères de zilpaterol.

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