C - Chemistry – Metallurgy – 03 – B
Patent
C - Chemistry, Metallurgy
03
B
150/11, 117/46.3
C03B 25/02 (2006.01) A61L 33/00 (2006.01) B01D 39/20 (2006.01) C03C 25/40 (2006.01) D04H 1/58 (2006.01) G01N 33/86 (2006.01)
Patent
CA 1262220
ABSTRACT The present invention provides coagulation- neutral, hydrophilic glass fibres, wherein on their surfaces are bound silanes according to the following structure glass Image wherein R1 is an alkylene radical containing 2 to 6 carbon atoms, X a hydroxyl group, an alkoxy radical optionally substituted by one or more hydroxyl groups or an amino acid or peptide residue and R'3 is either a lower alkyl radical or an oxygen bridge to the silicon atoms of the neighbouring group or to the glass surface; the silane bound glass fibres are produced by reacting clean glass fibres with a silane of the general formula: Image (I) wherein R1 is an alkylene radical containing 2 to 6 carbon atoms, R2 is an alkoxy radical containing up to 6 carbon atoms and R3 is an alkyl or alkoxy radical containing up to 6 carbon atoms, the oxiran group being converted into the group X by hydrolysis, alcoholysis or reaction with an amino acid or a peptide; the glass fibres may particularly be employed for the separation of plasma from blood for haemostasiological tests, especially in the form of a layer having an average diameter of 0.2 to 5µ and a density of 0.1 to 0.5 g./cm3..
513046
Freitag Helmut
Wielinger Hans
Boehringer Mannheim Gmbh
Swabey Ogilvy Renault
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