Thioalkanoyl amino acids

Details Thioalkanoyl amino acids Thioalkanoyl amino acids

C - Chemistry, Metallurgy

07

D

260/283, 260/287

C07D 215/42 (2006.01) C07D 311/68 (2006.01) C07D 317/70 (2006.01) C07D 339/04 (2006.01)

Patent

CA 1168233

ABSTRACT OF THE DISCLOSURE New bicyclic compounds of the formula: (I) Image wherein R1 and R2, which may be the same or different, each represents hydrogen, halogen, lower alkyl, hydroxyl, lower alkyloxy or aralkyloxy, or R and R2 jointly represent lower a!kylenedioxy; R3 and R4 each represents hydrogen or lower alkyl; R5 represents hydrogen, lower alkyl or -CH2SR7 (wherein R7 represents hydrogen or acyl); R represents hydrogen or acyl, or R6 and R7 jointly represent a single bond; X represents -CH2-, -O- or , ?NR8 wherein R8 represents hydrogen, acyl or lower alkyl); and n represents 2, 3 or 4, are disclosed, as well as salts thereof. The compounds (1) and their salts exhibit inhibitory activities of angiotensin converting enzyme and bradykinin decomposing enzyme, and are useful as antihypertensive agents.

372474

Affiliated with

Also associated with

Rating

Thioalkanoyl amino acids does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Thioalkanoyl amino acids, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Thioalkanoyl amino acids will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1288991