Combination of renal vasodilators and alpha 1-adrenergic or...

A - Human Necessities – 61 – K

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167/103.9

A61K 38/22 (2006.01)

Patent

CA 1322717

-26- ABSTRACT This invention relates to combinations and methods for the treatment of renal disease, cardio- vascular disease and hypertension. More particularly, the invention relates to combinations of renal vaso- dilators and .alpha.1-adrenergic or ganglionic blocking agents. According to a preferred embodiment, atrio- peptins having renal vasodilator activity are used in combination with .alpha.1-adrenergic blocking agents for treating renal disease, cardiovascular disease and hypertension. The blocking agent promotes sus- tained renal vasodilation, thereby enhancing renal blood flow and kidney function.

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