Tuberculosis vaccines including recombinant bcg strains...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 1/21 (2006.01) A61K 35/74 (2006.01) A61K 39/04 (2006.01) A61P 31/04 (2006.01) C12N 9/00 (2006.01) C12N 9/06 (2006.01) C12N 9/88 (2006.01) C12N 15/52 (2006.01) C12N 15/53 (2006.01) C12N 15/60 (2006.01)

Patent

CA 2481108

The invention relates to a live recombinant Mycobacterium bovis-BCG strain comprising a nucleic acid capable of expression, the nucleic acid encoding at least one protein or polypeptide that exhibits alanine dehydrogenase activity, glutamine synthetase activity, or serine dehydratase activity.

L'invention concerne une souche vivante recombinée de Mycobacterium bovis-BCG comprenant un acide nucléique capable d'une expression, l'acide nucléique codant au moins une protéine ou un polypeptique présentant une activité alanine déshydrogénase, une activité glutamine synthétase, ou une activité sérine déshydratase.

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