Growth differentiation factor inhibitors and uses therefor

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/18 (2006.01) A01K 67/027 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 14/475 (2006.01) C07K 14/495 (2006.01) C12N 9/00 (2006.01) C12N 15/11 (2006.01) C12N 15/85 (2006.01) C12Q 1/00 (2006.01) C12Q 1/34 (2006.01) C12Q 1/48 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2359242

Inhibitors of GDF proteins, such as GDF-8 or GDF-11, are disclosed. Also disclosed are methods for identifying and using the inhibitors, for example, to generate transgenic animals and to treat a variety of diseases.

L'invention se rapporte à des inhibiteurs de protéines GDF growth differentiation factor, telles que GDF-8 et GDF-11. Elle se rapporte également à des procédés d'identification et d'utilisation de ces inhibiteurs dans le but, par exemple, de créer des animaux transgéniques et de traiter une variété de maladies.

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