Delivery of an active drug to the posterior part of the eye...

Details Delivery of an active drug to the posterior part of the eye... Delivery of an active drug to the posterior part of the eye...

A - Human Necessities

61

K

A61K 47/48 (2006.01)

Patent

CA 2531753

The present invention relates to method of sustained-delivery of and active drug to a posterior part of an eye of a mammal to treat or prevent a disease or condition affecting said mammal, wherein said disease or condition can be treated or prevented by the actin of said active drug upon said posterior part of the eye, comprising administering and effective amount of an ester prodrug of the active drug subconjuntivally or periocularly. Preferably, the active drug is more than about 10 times as active as the prodrug. Other aspects of this invention deal with the treatment of certain disease by the periocular or subconjuctival delivery of an ester prodrug, and certain pharmaceutical products containing ester prodrugs for periocular or subconjuctival administration.

L'invention concerne un procédé d'administration prolongée d'un médicament actif dans la partie postérieure d'un oeil d'un mammifère, en vue de traiter ou de prévenir une maladie ou un état affectant ledit mammnifère, ladite maladie ou le dit état pouvant être traité ou empêché sous l'effet dudit médicament actif sur ladite partie postérieure de l'oeil. Le procédé consiste à administrer, de manière sous-conjonctivale ou périoculaire, une quantité efficace d'un promédicament ester du médicament actif. De préférence, le médicament actif est environ 10 fois plus actif que le promédicament. D'autres aspects de l'invention concernent le traitement de certaines maladies, par administration perioculaire ou sous-conjonctivale d'un promédicament ester, ainsi que certains produits pharmaceutiques contenant lesdits promédicaments pour administration perioculaire ou sous-conjonctivale.

Affiliated with

Also associated with

Rating

Delivery of an active drug to the posterior part of the eye... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Delivery of an active drug to the posterior part of the eye..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Delivery of an active drug to the posterior part of the eye... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1506170