Production process for intravenous immune serum globulin and...

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A61K 38/12 (2006.01) A23J 1/00 (2006.01) A61K 35/14 (2006.01) C07K 16/00 (2006.01) C07K 16/06 (2006.01) C12N 7/04 (2006.01) C12N 7/06 (2006.01)

Patent

CA 2281938

A process for producing an intravenously-administrable gamma globulin solution substantially free of contaminating viruses by heat treating for viral inactivation and fractionating an impure gamma globulin solution and then treating the purified gamma globulin with a solvent-detergent for further viral inactivation.

L'invention concerne un procédé de production d'une solution de gammaglobuline à administration intraveineuse sensiblement exempte de contamination virale. Ce procédé consiste à soumettre à un traitement d'inactivation virale et à fractionner une solution de gammaglobuline impure puis à traiter la gammaglobuline purifiée avec un mélange solvant-détergent pour une inactivation virale complémentaire.

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