Bioactive surface coating

Details Bioactive surface coating Bioactive surface coating

A - Human Necessities

61

L

A61L 29/08 (2006.01) A01N 25/24 (2006.01) A61L 27/34 (2006.01) A61L 31/10 (2006.01) C08F 220/18 (2006.01) C08F 230/08 (2006.01)

Patent

CA 2226132

Disclosed is a process for coating a surface of a substrate to make the surface antibacterial, by graft copolymerizing: (i) at least one monomer of the general formula (I): R-(A)a (I), (wherein R is a mono- or diolefinically unsaturated organic radical, preferably a hydrocarbon radical, having the valence a, A is a carboxyl group -COOH, sulfuric acid group -- OSO2OH, sulfonic acid group -SO3H, phosphoric acid group -OPO(OH)2, phosphonic acid group -PO(OH)2, phosphorous acid group -OP(OH)2, a phenolic hydroxyl group or a salt of the group, and a is 1, 2 or 3) and (ii) at least one monomer having a group which is sensitive to UV radiation, under radiative induction onto an optionally activated substrate surface. Articles coated in this way can be used in the medical or biotechnical field.

On divulgue un procédé de revêtement de la surface d'un substrat pour rendre cette surface antibactérienne, par copolymérisation avec greffe : i) d'au moins un monomère de formule générale (I) : R-(A)a (I), (où R est un radical organique, de préférence hydrocarboné, mono- ou dioléfiniquement insaturé de valence a, A est un groupe carboxyle -COOH, un groupe acide sulfurique - OSO2OH, un groupe acide sulfonique -SO3H, un groupe acide phosphorique -OPO(OH)2, un groupe acide phosphonique -PO(OH)2, un groupe acide phosphoreux -OP(OH)2, un groupe hydroxyle phénolique ou un sel de ces groupes, et a est 1, 2 ou 3) et ii) d'au moins un monomère portant un groupe qui est sensible au rayonnement UV, sous induction radiative sur une surface de substrat facultativement activée. Les objets ainsi revêtus peuvent être utilisés dans le domaine médical ou biotechnique.

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