G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/569 (2006.01) G01N 37/00 (2006.01)
Patent
CA 2561511
A method of monitoring microbes causing any infectious disease of experimental animal, comprising providing a microchannel chip having, immobilized thereon, molecules for detection of any antigen, antibody, etc. of microbes causing infectious diseases, effecting flow of a serum or body fluid collected from an experimental animal through minute flow passages of the chip, and detecting any antigen-antibody reaction on the chip. This method has realized rapid high- sensitivity detection in a closed system with the use of a minute amount of animal serum or body fluid for pathogenic microbe monitoring or inspection of any infectious disease of experimental animal.
Il est prévu un procédé de surveillance de microbes provoquant des maladies infectieuses d'animal d'expérimentation, consistant à fournir une puce à microcanal ayant, immobilisées sur celle-ci, des molécules pour détecter des antigènes, des anticorps, etc. de microbes provoquant des maladies infectieuses, provoquant l~écoulement d~un sérum ou d~un fluide corporel chez un animal d'expérimentation à travers des passages d~écoulements minuscules de la puce, et à détecter toute réaction antigène-anticorps sur la puce. Ce procédé permet une détection rapide haute sensibilité dans un circuit fermé en utilisant une quantité minime de sérum animal ou de fluide corporel pour surveillance des microbes pathogènes ou l~examen de toute maladie infectieuse d'animal d'expérimentation.
Aoki Hiroyoshi
Nagamune Teruyuki
Tajima Akihiko
Yamagata Yutaka
Fuence Co. Ltd.
Nagamune Teruyuki
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Riken
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