Process for production of prostaglandin intermediates

Details Process for production of prostaglandin intermediates Process for production of prostaglandin intermediates

C - Chemistry, Metallurgy

07

D

C07D 317/30 (2006.01) C07C 59/90 (2006.01) C07C 69/738 (2006.01) C07C 405/00 (2006.01) C07D 311/94 (2006.01) C07D 313/06 (2006.01) C07D 407/12 (2006.01)

Patent

CA 2077418

The present invention is directed to improving the isomer ratio of a cis-isomer as compared to the corresponding trans- isomer with respect to the 5-6 double bond in the production of prostaglandins. The improvement is achieved when a lactol is reacted with an ylide to cause simultaneous formation of the 5-double bond and an .alpha.-chain, whereby the ylide generated from a phosphonium salt with a potassium base, and a solvent which is liquid at the reaction temperature and has a dipole moment of 0.3 to 3.0D are used.

Affiliated with

Also associated with

Rating

Process for production of prostaglandin intermediates does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for production of prostaglandin intermediates, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for production of prostaglandin intermediates will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1592690