C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 15/24 (2006.01) A61K 31/485 (2006.01) A61K 31/519 (2006.01) A61K 31/7042 (2006.01) A61K 31/7064 (2006.01) A61P 25/04 (2006.01) C07D 239/18 (2006.01) C07D 249/14 (2006.01) C07D 487/04 (2006.01) C07D 489/02 (2006.01) C07H 7/06 (2006.01) C07H 17/00 (2006.01)
Patent
CA 2746701
The invention relates to compounds having formula (I) wherein: R1 represents a hydrogen atom or a (C1-C4)alkyl group; R2 represents a hydroxyl group, a thiol group, a (C1-C4)alkyloxy group or a thio(C1-C4)alkyl group; and n is an integer equal to 1 or 2, in the form of a base or acid addition salt, as well as in hydrate or solvate form. The invention also relates to the preparation method thereof and to the use of same in therapeutics.
La présente invention a pour objet les composés répondant à la formule (I) dans laquelle : R1 représente un atome d'hydrogène ou un groupe (C1-C4)alkyle, R2 représente un groupe hydroxyle, un groupe thiol, un groupe (C1-C4)alkyloxy ou un groupe thio(C1-C4)alkyle, et n est un nombre entier égal à 1 ou 2, à l'état de base ou de sel d'addition à un acide ainsi qu'à l'état d'hydrate ou de solvate. La présente invention vise également leur procédé de préparation et leur application en thérapeutique.
Dlubala Alain
Ripoche Isabelle
Trecant Claire
Robic
Sanofi
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