1-(2-oxo-acetyl)-piperidine-2-carboxylic acid derivatives as...

Details 1-(2-oxo-acetyl)-piperidine-2-carboxylic acid derivatives as... 1-(2-oxo-acetyl)-piperidine-2-carboxylic acid derivatives as...

C - Chemistry, Metallurgy

07

D

C07D 401/12 (2006.01) A61K 31/395 (2006.01) C07D 207/16 (2006.01) C07D 211/60 (2006.01) C07D 401/14 (2006.01) C07D 403/12 (2006.01) C07D 405/14 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01) C07D 471/04 (2006.01) C07D 473/00 (2006.01) C07D 487/04 (2006.01)

Patent

CA 2144962

The present invention relates to novel compounds of formula (I) which maintain, increase, or restore sensitivity of cells to therapeutic or prophylactic agents. This invention also relates to pharmaceutical compositions comprising these compounds. The compounds and pharmaceutical compositions of this invention are particularly well-suited for treatment of multi-drug resistant cells, for prevention of the development of multi-drug resistance and for use in multi-drug resistant cancer therapy.

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