A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/127 (2006.01) A61K 31/136 (2006.01) A61K 31/4375 (2006.01) A61K 31/475 (2006.01) A61K 47/24 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2673924
A liposomal pharmaceutical formulation comprising multivalent ionic drug, a process for the preparation thereof, and the use thereof in the treatment of diseases, wherein the particle size of the liposome is about 30-80 nm, and the phospholipid bilayer contains a phospholipid with Tm > body temperature thereby the phase transition of the liposome is above body temperature.
L'invention porte sur une composition pharmaceutique de liposome comprenant un médicament ionique polyvalent, et sur ses utilisations dans le traitement de maladies. La taille des particules de liposome est d'environ 30-80 nm, et la double couche de phospholipides contient un phospholipide où Tm > la température du corps; la transition de phase du liposome se fait ainsi au-dessus de la température du corps.
Guo Wenmin
Li Chunlei
Li Yanhui
Shen Dongmin
Wang Caixia
Osler Hoskin & Harcourt Llp
Shijiazhuang Pharma. Group Zhongqi Pharmaceutical Technology (sh Ltd.
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