Skin care composition

A - Human Necessities – 61 – K

Patent

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Details

A61K 8/67 (2006.01) A61K 8/365 (2006.01) A61Q 19/08 (2006.01)

Patent

CA 2318437

There are provided compositions which include a retinoid and preferably retinol; a dermatologically active acid; and a volatile base, such as ammonium hydroxide. Another embodiment of the invention includes compositions comprising a retinoid and preferably retinol; a dermatologically active acid; a volatile base; and a second neutralizing agent. There are also provided compositions which include a retinoid, a neutralized ammonium salt of a dermatologically active acid, and optionally a neutralized salt, other than ammonium salt, of an acid. Further provided are methods for reducing fine lines, wrinkles, skin roughness, and pore size and for increasing the clarity of a skin surface, cellular turnover, skin radiance, skin smoothness, skin permeation or collagen synthesis in a mammal in need thereof. Compositions as described above are administered topically to the skin of the animal.

L'invention concerne une composition renfermant : un rétinoïde, de préférence un rétinol ; un acide actif sur le plan dermatologique ; et une base volatile, telle qu'un hydroxyde d'ammonium. Un autre mode de réalisation de l'invention fait intervenir une composition comprenant : un rétinoïde, de préférence un rétinol ; un acide actif sur le plan dermatologique ; une base volatile ; et un second agent neutralisant. L'invention porte également sur une composition renfermant : un rétinoïde, un sel d'ammonium neutralisé d'un acide actif sur le plan dermatologique, et éventuellement un sel neutralisé, autre que le sel d'ammonium, d'un acide. L'invention propose en outre des méthodes permettant de réduire les ridules, les rides, la rugosité de la peau et la taille des pores, et permettant d'améliorer la clarté de la surface de la peau, le renouvellement cellulaire, la pénétration de la peau ou la synthèse du collagène chez un mammifère. Les compositions décrites ci-dessus sont administrées sous forme de médicament topique.

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