C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 239/46 (2006.01) A61K 31/505 (2006.01) A61P 3/06 (2006.01) C07D 239/48 (2006.01) C07D 401/04 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01) C07D 413/12 (2006.01)
Patent
CA 2634676
The present invention relates to a compound of the general formula (1): (see formula 1) wherein, Y is a methylene group, and the like; A is an unsubstituted or substituted heterocyclic group, and the like; B is an unsubstituted or substituted phenyl group, and the like; R1 is an unsubstituted or substituted alkyl group, and the like; and R2 is an unsubstituted or substituted amino group, and the like; or a pharmaceutically acceptable derivative thereof, which has an inhibitory activity against cholesteryl ester transfer protein (CETP), thereby being useful for prophylaxis and/or treatment of arteriosclerotic diseases, hyperlipemia or dyslipidemia, and the like.
Cette invention concerne un composé représenté par la formule (1) dans laquelle Y désigne un groupe méthylène et analogue; A désigne un groupe hétérocyclique éventuellement substitué et analogue; B désigne un groupe phényle éventuellement substitué et analogue; R1 désigne un groupe alkyle éventuellement substitué et analogue; et R2 désigne un groupe amino éventuellement substitué et analogue; ou un dérivé pharmaceutiquement acceptable de celui-ci, qui présente une activité inhibitrice contre la protéine de transfert d'ester de cholestéryle (CETP), ce qui le rend utile pour la prophylaxie et/ou le traitement de maladies artériosclérotiques, de l'hyperlipémie ou de la dyslipidémie, et analogue.
Hayashi Norimitsu
Higashijima Takanori
Kubota Hitoshi
Nakamura Yoshinori
Oka Kozo
Kirby Eades Gale Baker
Mitsubishi Tanabe Pharma Corporation
LandOfFree
Trisubstituted amine compounds as inhibitors of cholesteryl... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Trisubstituted amine compounds as inhibitors of cholesteryl..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Trisubstituted amine compounds as inhibitors of cholesteryl... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1727168