Methods and compositions for treatment of bone defects with...

Details Methods and compositions for treatment of bone defects with... Methods and compositions for treatment of bone defects with...

C - Chemistry, Metallurgy

12

N

C12N 5/077 (2010.01) A61K 35/12 (2006.01) A61P 19/00 (2006.01) A61L 27/38 (2006.01)

Patent

CA 2667359

Provided herein are methods of using adherent placental stem cells and placental stem cell populations, and methods of culturing, proliferating and expanding the same. Also provided herein are methods of differentiating the placental stem cells. Further provided herein are methods of using the placental stem cells to formulate implantable or injectable compositions suitable for administration to a subject. Still further provided herein are provides methods for treating bone defects with stem cells and compositions comprising stem cells.

L'invention concerne des procédés d'utilisation de cellules souches placentaires adhérentes et de populations de cellules souches placentaires, ainsi que des procédés de culture, de prolifération et d'expansion de celles-ci. L'invention concerne en outre des procédés de différenciation de cellules souches placentaires. De plus, l'invention concerne des procédés d'utilisation des cellules souches placentaires en vue de formuler des compositions implantables ou injectables, convenant pour l'administration à un sujet. Enfin, l'invention concerne des procédés de traitement de déficits osseux au moyen de cellules souches, ainsi que des compositions comprenant des cellules souches.

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