Method and means for prevention of cataract

A - Human Necessities – 61 – K

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A61K 31/557 (2006.01) A61K 31/5575 (2006.01)

Patent

CA 2175595

The use of thiol-binding prostaglandins or prostaglandin-like compounds for manufacturing a composition for prevention of cataract is described as well as a method of using such compounds for prevention of cataract. Preferred compounds are those with an alpha beta unsaturated ketone in the ring, especially PGA and PGJ and derivatives thereof, or one or more alpha beta unsaturated ketones in the alpha and/or omega chain.

Utilisation de prostaglandines fixant le thiol ou de composés analogues à la prostaglandine pour produire une préparation préventive de la cataracte, et méthode d'utilisation desdits composés pour prévenir la cataracte. Les composés préconisés sont ceux dont le cycle comporte soit une cétone alpha-béta insaturée et plus particulièrement les PGA et PGJ et leurs dérivés, soit une ou plusieurs cétones alpha-béta insaturées dans la chaîne alpha et/ou oméga.

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