C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/42 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) A61P 9/00 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2378451
The invention concerns the use of anti-idiotypic antibodies of the fibroblast growth factor (1) and/or anti-idiotypic antibodies of the fibroblastic growth factor (2), for preparing a medicine for treating pathologies involving endothelial cells implied in an angiogenic process, either for inhibiting angiogenesis, or for promoting angiogenesis, without affecting the quiescent endothelial cells, or for preparing a diagnostic product for pathologies involving endothelial cells implied in an angiogenic process.
La présente invention a pour objet l'utilisation d'anticorps anti-idiotypiques du facteur de croissance fibroblastique (1) et/ou d'anticorps anti- idiotypiques du facteur de croissance fibroblastique (2), pour la préparation d'un médicament destiné au traitement de pathologies impliquant des cellules endothéliales engagées dans un processus d'angiogénèse, soit pour inhiber l'angiogénèse, soit pour favoriser l'angiogénèse, sans affecter les cellules endothéliales quiescentes, ou pour la préparation d'un produit de diagnostic de pathologies impliquant des cellules endothéliales engagées dans un processus d'angiogénèse.
Jouanneau Jacqueline
Malavaud Bernard Andre
Plouet Jean
Savagner Pierre
Sordello Sylvie
Centre National de La Recherche Scientifique
Fetherstonhaugh & Co.
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