A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/445 (2006.01) A61K 31/38 (2006.01) A61K 31/40 (2006.01) A61K 31/4025 (2006.01) A61K 31/4535 (2006.01) A61K 31/55 (2006.01)
Patent
CA 2211530
A method of lowering serum calcium levels comprising administering to a human in need thereof an effective amount of a compound having formula (I), wherein R1 and R3 are independently hydrogen, -CH3, (a), or (b), wherein Ar is optionally substituted phenyl; R2 is selected from the group consisting of pyrrolidine, hexamethyleneimino, and piperidino; or a pharmaceutically acceptable salt of solvate thereof.
Procédé de réduction des niveaux de calcium sérique, consistant à administrer à une personne nécessitant un tel traitement une dose efficace d'un composé de la formule (I) dans laquelle R<1> et R<3> représentent indépendamment hydrogène, -CH3, (a) ou (b), Ar représentant phényle éventuellement substitué; R<2> est choisi dans le groupe composé de pyrrolidine, hexaméthylène-imino et pipéridino; ou un sel ou solvate pharmaceutiquement acceptable de ce composé.
Boss Susan Margaret
Dere Willard Honglen
Eli Lilly And Company
Gowling Lafleur Henderson Llp
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