Preparation and utility of substituted erythromycin analogs

Details Preparation and utility of substituted erythromycin analogs Preparation and utility of substituted erythromycin analogs

C - Chemistry, Metallurgy

07

H

C07H 17/08 (2006.01) A61K 31/7048 (2006.01) A61K 31/7052 (2006.01) A61P 1/04 (2006.01) A61P 31/04 (2006.01)

Patent

CA 2654450

The present disclosure is directed to novel macrolide antibiotics of Formula (I) and pharmaceutically acceptable salts and prodrugs thereof; and the chemical syntheses and medical uses of these novel macrolide antibiotics for the treatment and/or management of infections caused by various aerobic and anaerobic gram-positive and gram-negative microorganisms as well as various mycobacteria.

La présente invention concerne de nouveaux antibiotiques macrolides de formule (I) et des sels et promédicaments pharmaceutiquement acceptables de ceux-ci ; et la synthèse chimique et les utilisations médicales de ces nouveaux antibiotiques macrolides pour le traitement et/ou le contrôle d'infections causées par différents micro-organismes aérobies et non aérobies, Gram positif et Gram négatif ainsi que différentes mycobactéries.

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