Steroid solution aerosol products with enhanced chemical...

A - Human Necessities – 61 – K

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A61K 9/12 (2006.01) A61K 31/57 (2006.01) A61K 31/573 (2006.01) A61K 31/58 (2006.01) B65D 83/14 (2006.01)

Patent

CA 2371931

A medicinal aerosol steroid solution formulation product with enhanced chemical stability. The steroid is a 20-ketosteroid having an OH group at the C-17 or C-21 position and the aerosol container has a non-metal interior surface which has been found to reduce chemical degradation of such steroids.

Cette invention concerne un produit médicinal qui consiste en une formulation d'une solution de stéroïde en aérosol, et qui possède une meilleure stabilité chimique. Le stéroïde consiste en un 20-kétostéroïde comportant un groupe OH à la position C-17 ou C-21. Le conteneur aérosol possède une surface interne non métallique qui permet, comme on l'a découvert, de réduire la dégradation chimique de ces stéroïdes.

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