C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 405/04 (2006.01) A61K 31/513 (2006.01) A61K 31/52 (2006.01) C07D 473/28 (2006.01) C07D 473/30 (2006.01) C07D 473/34 (2006.01) C07D 473/40 (2006.01)
Patent
CA 2632280
This invention relates to certain unsaturated fatty acid derivatives of therapeutically active 1,3-dioxolane nucleoside analogues and to pharmaceutical formulations containing them. The said derivatives are referred to as "Compounds of formula (I)" herein. Compounds of formula (I) can be used in the treatment of a cancerous disease. Treatment of both solid tumours and haematological cancers such as leukaemias, lymphomas and multiple myelomas are included.
La présente invention concerne certains dérivés d'acides gras insaturés d'analogues thérapeutiquement actifs de nucléosides de type 1,3-dioxolanne, ainsi que des formules pharmaceutiques les incluant. Lesdits dérivés sont appelés « Composés de formule (I) » dans la présente invention. Les composés de formule (I) peuvent être employés dans le traitement d'une maladie cancéreuse. L~invention inclut le traitement de tumeurs solides et de cancers hématologiques tels que les leucémies, les lymphomes et les myélomes multiples.
Eriksen Ole Henrik
Hagen Steinar
Liland Sandvold Marit
Myhren Finn
Clavis Pharma Asa
Fetherstonhaugh & Co.
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