Diagnostic assay for endometriosis

Details Diagnostic assay for endometriosis Diagnostic assay for endometriosis

G - Physics

01

N

G01N 33/564 (2006.01)

Patent

CA 2406288

The present invention provides a method for detecting endometriosis in a patient and is an improvement over invasive and expensive surgical procedures. The method employs immunoassays which detect autoantibodies in a serum sample which react with Thomsen-Friedenreich antigen (Tf). Increased levels of autoantibodies in a serum sample from the patient which bind to Tf-like antigen is indicative of endometriosis in the patient.

La présente invention, qui concerne une méthode de détection d'une endométriose chez une patiente, constitue un progrès par rapport à des techniques invasives et chirurgicales coûteuses. Cette méthode repose sur des dosages immunologiques permettant de détecter dans un échantillon de sérum des anticorps qui réagissent avec un antigène de Thomsen-Freidenreich (Tf). Des niveaux accrus d'auto-anticorps dans un échantillon de sérum qui se lient à un antigène de type Tf permettent de conclure à la présence d'une endométriose.

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