Helical cytokine zalpha33

Details Helical cytokine zalpha33 Helical cytokine zalpha33

C - Chemistry, Metallurgy

12

N

C12N 15/19 (2006.01) C07K 14/52 (2006.01) C07K 16/24 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2387371

Novel cytokine polypeptides, materials and methods for making them, and method of use are disclosed. The polypeptides comprise at least nine contiguous amino acid residues of SEQ ID NO:2 or SEQ ID NO:4, and may be prepared as polypeptide fusions comprise heterologous sequences, such as affinity tags. The polypeptides and polynucleotides encoding them may be used within a variety of therapeutic, diagnostic, and research applications.

Cette invention concerne de nouveaux peptides à base de cytokine, des matériaux et des procédés servant à leur production, ainsi qu'un procédé d'utilisation. Ces polypeptides comprennent au moins neuf résidus d'acide aminé contigus qui correspondent au N· ID SEQ : 2 ou au N· ID SEQ : 4. Ces polypeptides peuvent être préparés sous forme de fusions de polypeptides comprenant des séquences hétérologues, telles que des marqueurs d'affinité. Ces polypeptides ainsi que les polynucléotides qui les codent peuvent être utilisés dans diverses applications thérapeutiques, diagnostiques et de recherche.

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