1,1,2-triphenyl-ethane or ethylene compounds

Details 1,1,2-triphenyl-ethane or ethylene compounds 1,1,2-triphenyl-ethane or ethylene compounds

C - Chemistry, Metallurgy

07

C

260/293, 260/360

C07C 39/00 (2006.01) C07C 29/09 (2006.01) C07C 29/10 (2006.01) C07C 29/128 (2006.01) C07C 33/26 (2006.01) C07C 33/28 (2006.01) C07C 39/12 (2006.01) C07C 39/21 (2006.01) C07C 39/367 (2006.01) C07C 39/373 (2006.01) C07C 43/178 (2006.01) C07C 43/225 (2006.01) C07C 43/23 (2006.01) C07D 295/092 (2006.01) C07D 295/10 (2006.01) C07D 307/06 (2006.01) C07D 307/12 (2006.01) C07D 307/14 (2006.01) C07D 307/42 (2006.01) C07D 309/04 (2006.01) C07D 309/12 (2006.01)

Patent

CA 1185977

ABSTRACT OF THE DISCLOSURE Novel alkane and alkene derivatives and their non-toxic pharma- ceutically acceptable salts are provided herein. The compounds are of the general formula Image (I) or Image (II) wherein n, R1, R2, R3, R4, and R5 are as specifically defined in the specification. The compounds and their non-toxic salts and esters exhibit valuable pharmacological properties as estrogenic, anti-estrogenic, progestanic and anti-tumour activity. Certain compounds of the group are useful as chemical intermediates for the preparation of pharmacologically active compounds of the invention.

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