1h-thieno[2,3-c]pyrazole derivatives useful as kinase...

Details 1h-thieno[2,3-c]pyrazole derivatives useful as kinase... 1h-thieno[2,3-c]pyrazole derivatives useful as kinase...

C - Chemistry, Metallurgy

07

D

C07D 495/04 (2006.01) A61K 31/4162 (2006.01) A61P 9/10 (2006.01) A61P 17/06 (2006.01) A61P 19/02 (2006.01) A61P 25/28 (2006.01) A61P 31/12 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2555262

Thieno[2,3-c]pyrazole derivatives of formula (I) and pharmaceutically acceptable salts thereof, as defined in the specification, process for their preparation and pharmaceutical compositions comrising them are disclosed; the compounds of the invention may be useful in therapy, in the treatment of diseases associated with a disregulated protein kinase activity, like cancer.

L'invention concerne des dérivés de thiéno[2,3-c]pyrazole de formule générale (I) et des sels acceptables sur le plan pharmaceutique de ceux-ci, dont la signification est indiquée dans la description ; ainsi qu'un procédé de préparation de ceux-ci et des compositions pharmaceutiques les contenant. Les composés de l'invention peuvent être utilisés en thérapie, dans le traitement de maladies associées à un dérèglement de l'activité de la protéine kinase, comme le cancer.

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