A microfluidic device and method for fabricating the...

B - Operations – Transporting – 81 – C

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B81C 1/00 (2006.01) B81B 1/00 (2006.01) G01N 21/64 (2006.01)

Patent

CA 2731413

The present application is directed to a technological platform with integrated microfluidic and optical modules for bio-detection. The platform enables in-situ detection by integrating fluidics with optical source and detection capabilities within a fabricated microchip. The platform is a polymer-based microfluidic chip having integrated excitation source and detection elements in a vicinity of a microfluidic reaction chamber configured to contain a micro-volume of a test sample. The principle of detection is based on an excitation source induced fluorescence of the test sample within the microfluidic reaction chamber.

La présente invention concerne une plate-forme technologique pourvue de modules microfluidiques et optiques intégrés pour la biodétection. La plate-forme permet la détection in situ en intégrant des éléments fluidiques dotés dune source optique et des capacités de détection à l'intérieur d'une micropuce manufacturée. La plate-forme est une puce microfluidique à base de polymère présentant une source d'excitation intégrée et des éléments de détection à proximité d'une chambre de réaction microfluidique configurée pour contenir un micro-volume d'un échantillon dessai. Le principe de la détection est basé sur une fluorescence induite par une source d'excitation de l'échantillon dessai à l'intérieur de la chambre de réaction microfluidique.

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