C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A01K 67/027 (2006.01) A61K 38/17 (2006.01) C07K 14/435 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C07K 19/00 (2006.01) C12N 15/63 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01)
Patent
CA 2446640
Novel proteins which bind human .szlig.-amyloid peptide, polynucleotides which encode these proteins, and methods for producing these proteins are provided. Diagnostic, therapeutic, and screening methods employing the polynucleotides and polypeptides of the present invention are also provided. Transgenic animals and knockout animals are also provided.
L'invention concerne des nouvelles protéines se liant au peptide .beta.-amyloïde, des polynucléotides codant pour ces protéines, et des méthodes de production de ces protéines. La présente invention concerne également des méthodes de diagnostic, de traitement et de criblage utilisant les polynucléotides et les polypeptides susmentionnés. Elle se rapporte en outre à des animaux transgéniques ainsi qu'à des animaux knock-out.
Bard Jonathan Adam
Howland David Scott
Jacobsen Jack Steven
Kajkowski Eileen M.
Ozenberger Bradley Alton
Torys Llp
Wyeth
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