(carboxyl)alkyloxyalkyl derivatives of cyclodextrins

Details (carboxyl)alkyloxyalkyl derivatives of cyclodextrins (carboxyl)alkyloxyalkyl derivatives of cyclodextrins

C - Chemistry, Metallurgy

08

B

C08B 37/16 (2006.01) A61K 31/715 (2006.01) A61K 47/48 (2006.01)

Patent

CA 2104097

2104097 9214762 PCTABS00015 Cyclodextrin ethers or mixed ethers wherein one or several hydroxy groups of the cyclodextrin moiety are etherified with mono- or dihydroxyalkyl and in the case of mixed ethers, one or more of the remaining hydroxy groups of the cyclodextrin moiety are further etherified with (carboxyl)alkyl or (derivatized carboxyl)alkyl, and wherein one or more of the hydroxy groups of said mono- or dihydroxyalkyl groups are further etherified with (carboxyl)alkyl or (derivatized carboxyl)alkyl; the alkylcarbonylated derivatives thereof; the non-toxic metal and amine salt forms thereof; and the stereochemically isomeric forms thereof. Process for preparing said cyclodextrin derivatives. Cyclodextrin derivatives obtainable by said process. Complexes and pharmaceutical compositions comprising said cyclodextrin derivatives.

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