Cell fusion assays using fluorescence resonance energy transfer

Details Cell fusion assays using fluorescence resonance energy transfer Cell fusion assays using fluorescence resonance energy transfer

C - Chemistry, Metallurgy

12

N

C12N 15/02 (2006.01) C12Q 1/00 (2006.01) C12Q 1/34 (2006.01) G01N 33/50 (2006.01) G01N 33/53 (2006.01) G01N 33/535 (2006.01) G01N 33/567 (2006.01)

Patent

CA 2398482

Methods of identifying inhibitors of the fusion of two types of cells, particularly when fusion is mediated by the interaction of a viral protein and such cellular proteins as CD4 and chemokine receptors, are disclosed. The methods are suitable for identifying substances that are useful for the treatment and prevention of viral diseases. Particularly preferred methods are useful for the identification of inhibitors of HIV-1 infection.

La présente invention concerne des procédés d'identification d'inhibiteurs de fusion de deux types de cellules, en particulier lorsque la fusion est exercée par l'interaction d'une protéine virale et des protéines cellulaires telles que CD4 et les récepteurs de la chimiokine. Ces procédés peuvent être utilisés pour identifier les substances utiles pour le traitement ou la prévention des maladies virales. Les procédés particulièrement préférés sont utiles pour l'identification des inhibiteurs de l'infection par le virus VIH-1.

Affiliated with

Also associated with

Rating

Cell fusion assays using fluorescence resonance energy transfer does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Cell fusion assays using fluorescence resonance energy transfer, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cell fusion assays using fluorescence resonance energy transfer will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1818426