Chemical process and new intermediates

Details Chemical process and new intermediates Chemical process and new intermediates

C - Chemistry, Metallurgy

07

D

C07D 209/42 (2006.01) C07C 45/46 (2006.01) C07C 45/63 (2006.01) C07C 49/84 (2006.01) C07C 323/22 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2430064

Process for the preparation of a compound of the general formula (I) and pharmaceutically acceptable salts and solvates thereof, (I) characterised by reacting an N-(amino-tioxo-methyl)-1H-indole-2-carboxamide of the general formula (II), with an .alpha.-halogen-ketone of the general formula (III), wherein X stands for halogen.

La présente invention concerne un processus de préparation d'un composé représenté par la formule générale (I) et des sels et solvates de celui-ci répondant aux normes pharmaceutiques. On fait réagir un N-(amino-tioxo-méthyle)-1H-indole-2-carboxamide représenté par la formule générale (II) avec un .alpha.-halogène-cétone représenté par la formule générale (III), dans laquelle X représente l'halogène.

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