C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 243/24 (2006.01) A61K 31/55 (2006.01) A61K 31/551 (2006.01) A61P 25/28 (2006.01) A61P 43/00 (2006.01) C07D 223/16 (2006.01) C07D 223/18 (2006.01) C07D 243/12 (2006.01) C07D 243/14 (2006.01) C07D 401/04 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 405/12 (2006.01) C07D 409/04 (2006.01) C07D 409/12 (2006.01) C07D 417/04 (2006.01)
Patent
CA 2325389
Disclosed are compounds which inhibit .beta.-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions that include a compound which inhibits .beta.-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.
L'invention concerne des composés inhibant la libération du peptide .beta.-amyloïde et/ou sa synthèse et présentant par conséquent une utilité dans le traitement de la maladie d'Alzheimer. L'invention concerne également des compositions pharmaceutiques comprenant un composé inhibant la libération du peptide .beta.-amyloïde et/ou sa synthèse ainsi que des méthodes de traitement de la maladie d'Alzheimer à la fois de façon prophylactique et thérapeutique à l'aide de ces compositions pharmaceutiques.
Audia James E.
Britton Thomas C.
Cwi Cynthia L.
Dressman Bruce A.
Henry Steven S.
Elan Pharmaceuticals Inc.
Eli Lilly & Company
Torys Llp
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