C - Chemistry – Metallurgy – 07 – F
Patent
C - Chemistry, Metallurgy
07
F
C07F 9/38 (2006.01) C07D 205/04 (2006.01) C07D 207/16 (2006.01) C07D 403/04 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01) C07D 413/10 (2006.01) C07D 413/14 (2006.01) C07F 9/572 (2006.01) C07F 9/6558 (2006.01)
Patent
CA 2472715
The present invention encompasses compounds of Formula I: as well as the pharmaceutically acceptable salts and hydrates thereof. The compounds are useful for treating immune mediated diseases and conditions, such as bone marrow, organ and tissue transplant rejection. Pharmaceutical compositions and methods of use are included.
La présente invention concerne des composés selon la formule I. Elle traite également de sels pharmaceutiquement acceptables et d'hydrates de ces derniers. Les composés permettent de traiter des états et des maladies d'origine immunologique comme les rejets de transplants de moelle osseuse, d'organes et de tissus. L'invention a aussi pour objet des compositions pharmaceutiques et des procédés d'utilisation.
Bugianesi Robert L.
Doherty George A.
Gentry Amy
Hale Jeffrey J.
Lynch Christopher L.
Merck & Co. Inc.
Merck Sharp & Dohme Corp.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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