A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/27 (2006.01) A61K 31/215 (2006.01) A61K 31/343 (2006.01) A61K 31/4025 (2006.01) C07D 307/92 (2006.01)
Patent
CA 2350213
Provided are, among other things, lipid-lowering or glucose-lowering methods and compounds, particularly lipid-lowering or glucose-lowering compounds, with an A-B ring structure as shown in formula (I): wherein the dotted line between carbons 5 and 6, the dotted line between carbon 4 and R2, and the dotted line between carbon 11 and R3 each independently represent an optional double bond from the respective numbered carbon to a linked carbon, and wherein X is hydroxy or, together with Y is oxy linking carbon 8 and carbon 12.
L'invention concerne, en autres choses, des méthodes et des composés hypolipémiants et hypoglycémiants, en particulier des composés hypolipémiants ou hypoglycémiants ayant une structure de cyle A-B (I), dans laquelle la ligne pointillée entre les atomes de carbone 5 et 6, la ligne pointillée entre l'atome de carbone 4 et R?2¿ ainsi que la ligne pointillée entre l'atome de carbone 11 et R?3¿ représentent chacune indépendamment une double liaison optionnelle à partir de l'atome de carbone à numéro respectif à un atome de carbone lié, et dans laquelle X représente hydroxy, ou avec Y, il représente oxy liant l'atome de carbone 8 et l'atome de carbone 12.
Egan John J.
Fang Sheng Ding
Lankin Michael
Resek John
Shih David H.
Alteon Inc.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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