C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/18 (2006.01) C07K 7/08 (2006.01) G01N 33/48 (2006.01) G01N 33/53 (2006.01) G01N 33/543 (2006.01) G01N 33/68 (2006.01)
Patent
CA 2482317
The present invention is directed toward determination of particular fragments of haptoglobin which are found in the circulation of patients suffering from Alzheimer's dementia; toward processes for diagnosing Alzheimer's disease via utilization of said haptoglobin fragments; and toward various methodologies for determining risk-assessment, disease progression, disease state, therapeutic avenues, and validation of pharmaceutical agents deemed to be efficacious in treating the disease.
L'invention concerne la détermination de fragments particuliers de l'haptoglobine qui sont découverts dans la circulation de patients souffrant de la démence d'Alzheimer; elle concerne également des procédés de diagnostic de cette maladie par le biais de l'utilisation desdits fragments, ainsi que diverses méthodologies permettant d'évaluer les risques, de déterminer la progression de la maladie, l'état pathologique et les solutions thérapeutiques, et de valider des agents pharmaceutiques jugés efficaces dans le traitement de la maladie.
Barker Lisa
Brothers Greg
Jackowski George
Kireeva Inga
Pinchev Deborah
Finlayson & Singlehurst
Syn-X Pharma Inc.
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