C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 221/14 (2006.01) A61K 31/47 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) A61K 31/54 (2006.01) A61K 31/695 (2006.01) C07D 401/00 (2006.01) C07D 401/04 (2006.01) C07D 403/00 (2006.01) C07D 405/00 (2006.01) C07D 409/00 (2006.01) C07D 413/00 (2006.01) C07D 417/00 (2006.01) C07D 471/02 (2006.01) C07D 487/08 (2006.01) C07D 491/06 (2006.01) C07D 497/06 (2006.01) C07D 498/06 (2006.01) C07D 519/00 (2006.01) C07F 7/10 (2006.01)
Patent
CA 2263301
Benzo[de]isoquinoline-1,3-diones which are selective inhibitors of bacterial DNA gyrase and DNA topoisomerase useful in antibacterial agents are described as well as methods for their preparation and formulation. Novel intermediates useful in the preparation of the final products are also described.
La présente invention concerne des benzo[de]isoquinoline-1,3diones constituant des inhibiteurs sélectifs des ADN-gyrases et ADN-topoisomérases bactériennes et convenant particulièrement comme antibactériens. L'invention concerne également des procédés d'élaboration de ces isoquinolones. L'invention concerne enfin des intermédiaires convenant particulièrement à l'élaboration de ces produits finis.
Amegadzie Albert Kudzoi
Carey Maureen Elizabeth
Domagala John Michael
Huang Liren
Micetich Ronald George
Macrae & Co.
Warner-Lambert Company
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