Liquid distribution system

B - Operations – Transporting – 81 – B

Patent

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Details

B81B 7/00 (2006.01) B01J 4/02 (2006.01) B01J 19/00 (2006.01) B01L 3/00 (2006.01) C07H 21/00 (2006.01) C07K 1/00 (2006.01) F04B 19/00 (2006.01) F15D 1/02 (2006.01) F17D 1/14 (2006.01) G01N 33/543 (2006.01) H02K 44/02 (2006.01) H02N 11/00 (2006.01) B01F 5/06 (2006.01)

Patent

CA 2204912

The present invention provides a liquid distribution system, which is useful in a number of contexts, including in accomplishing various synthetic, diagnostic and drug screening reactions. The distribution system can comprise an alpha reservoir (200A) and a beta reservoir (200B), a first set of parallel and adjacent first and second feeder channels (211A- 211B) and a second set of parallel and adjacent third and fourth feeder channels (211C-211D) which are offset from the first and second feed channels (211A-211B), wherein (a) the first (211A) and third (211C) feeder channels are connected to the alpha reservoir (200A) via a first connector channel (211A) that is situated above or below the second (211B) and fourth feeder channels (211D) and are independent of the beta reservoir and (b) the second (211B) and fourth feeder channels (211D) are connected to the beta reservoir via a second connector channel (211B) that it situated above or below the first and third feeder channels (211A and 211C) and are independent of the alpha reservoir (200A). The distribution system is preferably a microscale distribution system. Various particular mechanisms for controlling flow into a liquid distribution system are described.

La présente invention concerne un système de distribution de liquide qui pourrait être utile dans plusieurs domaines, notamment pour la réalisation de diverses réactions lors d'opérations de synthèse, de diagnostic, ou d'analyse de médicaments. Ce système de distribution se compose d'un réservoir alpha (200A) et d'un réservoir bêta (200B), d'un premier ensemble de canaux d'alimentation primaires et secondaires, parallèles et adjacents (211A-211B) et d'un second ensemble de canaux d'alimentation tertiaires et quaternaires, parallèles et adjacents, séparés des canaux d'alimentation primaires et secondaires (211A-211B), de sorte que (a) les canaux d'alimentation primaires (211A) et tertiaires (211C) sont reliés au réservoir alpha (200A) au moyen d'un canal de connexion primaire (211A) situé au-dessus ou au-dessous des canaux d'alimentation secondaires (211B) et quaternaires (211D), et sont indépendants du réservoir bêta et (b) les canaux d'alimentation secondaires (211B) et quaternaires (211D) sont raccordés au réservoir bêta au moyen d'un canal de connexion secondaire (211B) situé au-dessus ou au-dessous des canaux d'alimentation primaires et tertiaires (211A et 211C) et sont indépendants du réservoir alpha (200A). Ce système de distribution fonctionne de préférence à petite échelle. Divers mécanismes particuliers de régulation du débit de ce système de distribution sont présentés.

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