C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/11 (2006.01) A61K 31/711 (2006.01) A61K 45/00 (2006.01) A61K 48/00 (2006.01) A61P 37/08 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01) G01N 33/68 (2006.01)
Patent
CA 2406028
By collecting blood samples from healthy subjects and patients with allergic diseases and searching for a gene showing a difference in its expression by the differential method, a gene B1153 showing a significantly higher expression level in the patients is successfully isolated. It is found out that this gene is usable in examining allergic diseases and screening a candidate compound for remedies therefor.
L'invention porte sur un méthode d'étude de maladies allergiques consistant: à recueillir des échantillons de sang chez des patients sains et chez des patients atteints de maladies allergiques, à rechercher par un procédé différentiel un gène présentant une différence d'expression; et à isoler avec succès chez lesdits patients le gène B1153 présentant un niveau sensiblement plus élevé d'expression. On a découvert que ledit gène pouvait servir à l'étude des maladies allergiques et au criblage d'un composé candidat pouvant les traiter.
Imai Yukiho
Matsumoto Yoshiko
Nagasu Takeshi
Oshida Tadahiro
Sugita Yuji
Genox Research Inc.
Japan As Represented By General Director Of Agency Of National C
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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