Method of electrolytically depositing a pharmaceutical...

A - Human Necessities – 61 – L

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A61L 27/32 (2006.01) A61L 27/04 (2006.01) A61L 27/14 (2006.01) A61L 27/30 (2006.01) A61L 27/54 (2006.01) C25D 11/36 (2006.01)

Patent

CA 2574115

A method of electrolytically depositing a pharmaceutical coating onto a conductive osteal implant. The implant is submerged into an electrolytic cell containing an electrolysis solution of the pharmaceutical and acts as a cathode. When current is applied to the electrolytic cell, the pharmaceutical coating forms on the implant. The pharmaceutical can comprise bisphosphonates, including calcium salts. The implants can comprise any conductive material suitable for use as an osteal implant. The implants can also be electrolytically coated with calcium phosphate before coating with a pharmaceutical.

L'invention concerne un procédé permettant de déposer par voie électrolytique un enrobage pharmaceutique sur un implant osseux conducteur. L'implant est immergé dans une cellule électrolytique contenant une solution électrolytique de l'enrobage et agit comme une cathode. Lorsque l'on applique du courant sur la cellule électrolytique, l'enrobage pharmaceutique se forme sur l'implant. L'enrobage peut comprendre des biphosphonates, y compris des sels de calcium. Les implants peuvent être constitués de n'importe quel matériau conducteur pouvant être utilisé comme implant osseux. Les implants peuvent être également enrobés par voie électrolytique avec du phosphate de calcium avant l'enrobage.

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